Long-lasting immune response to a mild course of PCR-confirmed SARS-CoV-2 infection: A cohort study

This article by BBMRI.at partner Med Uni Graz presents findings from a cohort of COVID-19 convalescent individuals established and investigated with clinical partners at BBMRI.at partner Med Uni Graz / Biobank Graz.

Blood plasma, serum and buffy coat samples were collected from 326 non-hospitalized volunteers to determine pan-IG antibody titre. In addition, data on clinical symptoms of COVID-19, demographic characteristics, lifestyle, and comorbidities were gathered by e-questionnaire.

The results indicate a persistent and strong immune response against SARS-CoV-2 infection in those individuals with a mild course of COVID-19.

The authors found that also individuals without core symptoms developed immunity against COVID-19, but to a lower degree than individuals with core symptoms.

 

Kral, S.; Banfi, C.; Niedrist, T. et al.: Long-lasting immune response to a mild course of PCR-confirmed SARS-CoV-2 infection: A cohort study. Journal of Infection, Letter to the editor (2021) https://doi.org/10.1016/j.jinf.2021.08.030