Biobanking & laboratory services offered by BBMRI.at biobanks & partners
BBMRI.at biobanks aim to support researchers who work or intend to work with biological material and associated data. They want to make the researchers’ life easier and assist them with biobanking expertise in various steps along the biobanking workflow.
Biobanks provide access to samples and associated data and/or link researchers with principal investigators of sample/data cohorts for potential collaborations in industry or EU-funded projects.
BBMRI.at partner biobanks also offer several services and collaborate well with various partners to expand their service portfolio.
Services of BBMRI.at Biobank Partners
Providing access to samples and data
- Animal samples and data (cat, dog, ferret, guinea pig, hamster, horse, monkey, mouse, pig, rat sheep)
- Human samples and data
- Paraffin blocks (FFPE)
- Paraffin sections (slide mounted, unstained)
- Liquid samples (serum, EDTA-plasma, Li-Hep plasma, Na-Citrat plasma Buffy coat, urine, whole blood, saliva, follicular fluid, seminal plasma, synovia fluid, cerebrospinal fluid, feces, ascites, PBMC´s)
- Fresh frozen tissue
- Frozen tissue sections (e.g. slide mounted or in vials for nucleic acid analysis)
- Histochemical slides (e.g. H&E, CAB, …)
- Immunohistochemical slides
- Whole slide images (i.e. digital images of (Immuno)histochemical slides)
- Tissue micro array paraffin blocks
- Tissue micro array paraffin sections
- Primary cells and tissue culture
- Other sample types (e.g. isolated RNA, DNA, protein, …)
Sample processing
- Processing of sample types mentioned above
Sample storage capacities
- 24/7 temperature controlled sample storage at various conditions
- Long-term storage of archived samples
- Ultra-low freezer (-70°C to -90°C) 24/7 controlled
- Vapor phase liquid nitrogen (-135°C to -196°C) 24/7 controlled
Supporting research projects
- Supporting researchers during sample access process
- Supporting researchers during ethics application for a specific project
- Prospective sample collection (planning)
- Prospective sample collection/processing/storage/sample management (realization)
- Establishment of prospective sample collections according to ISO /CEN/TS standards (e.g. ISO
20166; ISO 20184, ISO 20186, etc.) - Supporting researchers concerning latest (pre-analytical) quality standard requirements
- Pathological evaluation and selection of appropriate cases
- Organization of sample/data transfer
Related infrastructure & equipment
- Shared-use of biobank equipment/lab space for researchers
- BSL2 Lab
- BSL3 Lab
- Various (local) partners with specialized equipment, expertise and service offers (e.g. core facilities)
Consultancy on topics related to biobanking
- Laboratory medicine (selection of appropriate anticoagulants, storage conditions, etc…)
- Study design
- Quality management and quality control
- ISO Standards (and CEN/TS) in biobanking
- Implementation of standards and SOPs in biobanking processes
- Data management
- Ethical issues & legal issues
- Project management
- Statistics
- Budgeting and business planning
Services for donors
- Processing withdrawals of biobank informed consents
- Biobank on site tours for the public
Data management
- Development of research cohort database
- Guide for anonymization & pseudonymization (in German)
Services related to infectious diseases
- Virus, RNA, DNA, protein isolation
- Whole genome sequencing
- Neutralization tests etc.
Services related to cancer research
- Whole exome sequencing
- Whole genome sequencing
- Digital pathology – mass scanning for whole slide imaging
- Metabolomics
- Lipidomics
- Isolation/Establishment of patient derived cell lines (short and long term cultures)
- Isolation/Establishment of cancer-associated fibroblasts from the same patient
- Cell culture 3D models
Further services
- Contact to and networking with other biobanks
- Education and training courses in biobanking
- Biobank on site tours for experts (e.g. researcher, medical doctors, cooperation partners etc.)
