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Biobanks, specimens, IVDR & standards
Recorded Presentation
The importance of the quality of biospecimens to generate reliable and reproducible research data
The rapid development and tremendous growth of the omics technologies have led to highly sensitive test systems and the generation of data of highest precision. With the higher sensitivity, however, a new influencing factor arose: the handling of biospecimens during the pre-analytical phase. Already the smallest variations in the biospecimen collection process, e.g. prolonged ischemia times or fixation, generate deviant results. Thus, pre-analytical factors turned out to be a major cause why promising results in biomarker research failed in the process of validation, as data were not reproducible on a large scale, thereby wasting time and money.
The Austrian academic biobank partners of BBMRI.at collecting and storing biospecimens are able to support researchers with high-quality biospecimens and associated clinical data together with information about the pre-analytical handling process. In addition, we also offer know-how about state-of-the-art collection, processing and storage of biological samples. We aim to make the "black box" of sample management transparent to help creating the basis for a better reproducibility of scientific data.