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"KIWI" stands for "Kinderwunsch Institut" (Fertility Institute) and represents a cohort consisting of prospectively collected body fluids and data from infertile couples during assisted reproductive technology.

The collection helps to elucidate the mechanisms of infertility and improve the success of fertility treatments in assisted reproductive technology (ART).

The "KIWI cohort" comprises samples of blood serum, follicular fluid, cumulus cells, embryo culture supernatant and seminal plasma and associated data. It includes male and female patients ranging from 18 to 45 years who are referred to the fertility clinic "Das Kinderwunsch Institut Schenk GmbH" in Dobl, Austria within the process of ART treatment.

More about sample types and quality in our BBMRI.at Catalogue >>

(C) Medical University of Graz

Disease Area

Research Area

Infertility (primary, secondary), fertility treatment, assisted reproductive technology

Sample Types

Blood serum, follicular fluid (collected per oocyte with special needle, i.e. Steiner-TAN-Needle), cumulus cells, embryo culture supernatant and seminal plasma.

Cohort Size

   > 500 couples

   Collection start in 2013 - collection ongoing

Donors

• Patients with fertility treatment
• Age: 18 to 45
• Gender: female and male

Associated Data

  Demographic data, endocrine profiles and monitored stimulation;

Every sample can be linked to oocyte pick up, embryo development (e.g. embryo morphokinetics) and treatment outcome

Informed Consent

   Broad Biobank IC (view template >>)

Access

   Cooperation  preferred

Quality Standards

• Sample quality of serum samples: CEN/TS 16945:2016 - Molecular in vitro diagnostic examinations. Specifications for pre-examination processes for metabolomics in urine, venous blood serum and plasma
• Quality management: ISO 9001:2015 (SOPs)

Contact

• Principle investigator:
  • Dr. Michael Schenk, MAS
  • Das Kinderwunsch Institut Schenk GmbH
  • FRED Fertility Research Education and Development GmbH
• Email: biobank-pm@medunigraz.at, michael.schenk@kinderwunsch-institut.at