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"COVID-19 Convalescent Cohort":
BBMRI.at Partner's Sample Collection Profile
"COVID-19 Convalescent Cohort"
The "COVID-19 Convalescent Cohort" is a sample collection at Biobank Graz (Med Uni Graz) which is based on a prospective sample cohort for current research on SARS-CoV-2.
Biobank Graz recruited participants (from Austria) who had recovered from COVID-19 and grouped them into two sub cohorts (see profile table). Volunteers were invited to fill in a questionnaire and donate various types of samples at different time points (see study design and table).
This cohort serves for:
- the development and validation of new antibody tests and neutralization assays
- the investigation of antibody titres over time
- a better characterization of the course of COVID-19
- the identification of diagnostic or prognostic biomarkers
Study design:
Participants are invited five times, i.e. 1st visit (time point 0), 2nd visit (after 1 month), 3rd visit (after 2 months), 4th visit (after 5 months), 5th visit (after 12 months), where the samples are collected. At the 1st visit, donors also fill in a questionnaire concerning symptoms, comorbidities, pre-history and lifestyle.
Disease Area Research Area | COVID-19 recovered patients, SARS-CoV-2, PCR test, antibody test |
Sample Types | serum, EDTA buffy coat, EDTA plasma, lithium heparin plasma, sodium citrate plasma, saliva and nasopharyngeal swabs (stored at -80 °C) |
Cohort Size | 23.739 aliquots from 364 participants as of March 10th |
Donors | volunteers who recovered from COVID-19
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Associated Data |
Data concerning symptoms, comorbidities, prehistory and lifestyle are collected via questionnaire
PCR tests and antibody tests are performed |
Informed Consent | Broad Biobank IC (view template de>>; view template en>>), sStudy specific IC |
Access | As of now |
Quality Standards |
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Contact
Publications
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Kral S, Banfi C, Niedrist T, Sareban N, Guelly C, Kriegl L, Schiffmann S, Zurl C, Herrmann M, Steinmetz I, Schlenke P, Berghold A, Krause R. Long-lasting immune response to a mild course of PCR-confirmed SARS-CoV-2 infection: A cohort study. J Infect. 2021 Nov;83(5):607-635. doi:
Niedrist T, Drexler C, Torreiter PP, Matejka J, Strahlhofer-Augsten M, Kral S, Riegler S, Gülly C, Zurl C, Kriegl L, Krause R, Berghold A, Steinmetz I, Schlenke P, Herrmann M. Longitudinal comparison of automated SARS-CoV-2 serology assays in assessing virus neutralization capacity in COVID-19 convalescent sera. Arch Pathol Lab Med. 2022 Jan 27. doi: 10.5858/arpa.2021-0604-SA. Epub ahead of print. PMID: 35085385
Eva M. Matzhold, Günther F. Körmöczi, Chiara Banfi, Marlies Schönbacher, Camilla Drexler, Helmberg, Ivo Steinmetz, Andrea Berghold, Peter Schlenke, Gabriel E. Wagner,
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View this and other cohorts from Biobank Graz in the BBMRI-ERIC Directory >>